Caspase 9 homologs have been identified in all mammals for which they are known to exist such as mus musculus and pan troglodytes. Parp 1 was originally identified as an apoptotic substrate for caspase 3 31 but more recent studies have shown that caspase 7 is also involved in the cleavage process 39. Interestingly nuclei of jurkat cells expressing gfp lamin a behaved like hela nuclei in the extracts.
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